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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 6.36
Human Site: S96 Identified Species: 10.77
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S96 L V I S Q M G S K K K P K I I
Chimpanzee Pan troglodytes XP_528522 404 44489 V96 K K E T S P Q V K G E E M P A
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S96 L V I S Q M S S K K K P K I I
Dog Lupus familis XP_548392 428 46939 K94 V S Q T D S K K Q P G I T Q Q
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 D108 P L V S Q M D D K M H P Q I I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 K105 T S R A G P R K P R K P S P R
Chicken Gallus gallus XP_001236410 416 45873 S94 D R G P T A H S P P L A K V K
Frog Xenopus laevis Q91560 421 46679 K94 T L A K C P K K D Q K V S E K
Zebra Danio Brachydanio rerio XP_002665913 418 47625 R112 D S H K P E K R F K K A K E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 D27 K R I M D K K D N K N T Q R M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 N95 D S G M S S G N D E T P Q L P
Poplar Tree Populus trichocarpa XP_002300407 274 31114 W23 K L P I N P N W A Q L Q Q T L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 K38 R N V K K V S K T V N V S S T
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 S94 K M G G N V Q S K P T T S S S
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 6.6 93.3 0 N.A. 46.6 N.A. N.A. 13.3 13.3 6.6 20 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 20 93.3 20 N.A. 66.6 N.A. N.A. 26.6 20 20 20 N.A. N.A. 26.6 N.A. 40
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 0 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 26.6 N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 0 0 8 0 0 15 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 0 0 0 15 0 8 15 15 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 8 8 8 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 22 8 8 0 15 0 0 8 8 0 0 0 0 % G
% His: 0 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 22 8 0 0 0 0 0 0 0 8 0 22 22 % I
% Lys: 29 8 0 22 8 8 29 29 36 29 36 0 29 0 15 % K
% Leu: 15 22 0 0 0 0 0 0 0 0 15 0 0 8 8 % L
% Met: 0 8 0 15 0 22 0 0 0 8 0 0 8 0 8 % M
% Asn: 0 8 0 0 15 0 8 8 8 0 15 0 0 0 0 % N
% Pro: 8 0 8 8 8 29 0 0 15 22 0 36 0 15 8 % P
% Gln: 0 0 8 0 22 0 15 0 8 15 0 8 29 8 8 % Q
% Arg: 8 15 8 0 0 0 8 8 0 8 0 0 0 8 8 % R
% Ser: 0 29 0 22 15 15 15 29 0 0 0 0 29 15 8 % S
% Thr: 15 0 0 15 8 0 0 0 8 0 15 15 8 8 15 % T
% Val: 8 15 15 0 0 15 0 8 0 8 0 15 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _